JW
Practitioner
Human study · 2 sources
Melatonin is not only a sleep hormone
Melatonin as a sleep hormone is the least interesting thing about melatonin. The mitochondrial pool is produced locally, at concentrations well above serum, and behaves like an antioxidant system rather than a circadian signal.
Methodological caution: a lot of this work is in vitro at concentrations no oral dose reaches. I'm flagging my own citation as preclinical for exactly that reason. #epistemics
Methodological caution: a lot of this work is in vitro at concentrations no oral dose reaches. I'm flagging my own citation as preclinical for exactly that reason. #epistemics
Research · Clinical study
Melatonin as an antioxidant: under promises but over delivers.
Journal of pineal research · 2016 · PUBMED 27500468
Research · Review
Is Melatonin the "Next Vitamin D"?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements.
Nutrients · 2022 · PUBMED 36235587